Prof. Dr. Atta-ur-Rahman E-mail: atta.rahman@iccs.edu |
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Prof. Dr. M. Iqbal Choudhary N.I.,S.I.,T.I. E-mail: iqbal.choudhary@iccs.edu |
Over 330 research publications in top international journals. seven national and international patents and eight books published and circulated internationally. Editor-in-Chief of a European science journal. Current research interests include search for new bioactive natural products from medicinal plants. marine animals and microorganisms, biotransformational studies on bioactive compounds, enzyme inhibition studies. and biological screening of antioxidant chemical compounds.
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Prof. Dr. Sheikh Arshad Saeed H.I. E-mail: arshad.saeed@iccs.edu |
Over 255 research research publications, 260 research abstracts and communications and 14 international patents. He is also the Visiting Professor of Pharmacology, Aga Khan University, Fellow of the Pakistan Academy of Medical Sciences and Fellow of the Royal Institute of Biology, London. Research interests include lipoproteins and other inhibitors of eicosanoid synthesis and mechanisms: role in atherosclerosis, inflammation, pregnancy and parturition, molecular mechanisms of human platelet activation and arachidonic acid metabolism, regulation in ischaemic heart disease, stroke and hypertension.
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Prof. Dr. Muhammad Anwar Waqar S.I.,T.I. E-mail:anwar_waqar@hotmail.com |
Over 140 research publications in international journals of repute, member of editorial boards of various scientific journals and promotion committees of international universities. Current research interests include role of urinary modulators in urolithiasis, evaluation of herbal reparations for kidney stones, allergies, asthma and inhalant allergens and elucidation of free radical scavengers in animal models.
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Prof. Dr. Ahsana Dar E-mail:ahsana.dar@iccs.edu; |
Over 30 research publications. Research interests include evaluation of synthetic compounds, natural products (marine / terrestrial) and herbal preparations for depression and other neurological disorders, cancer and inflammation. A variety of in vitro and in vivo assays and HPLC techniques etc. are employed to assess the aforementioned activities.
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Prof. Dr. Nurul Kabir E-mail:nkabir1@hotmail.com; |
Over 11 research publications in top-quality international journals. Research interests include cell biology observed by high-resolution light microscopy in diverse fields such as neurobiology, liver toxicity, embryology and immunology; exploring novel natural products for treatment of Parkinsonism or Paracetamol-induced liver injury by using differential interference contrast (DIC), multi-channel fluorescence and deconvolution microscopy.
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Prof. Dr. Kaneez Fatima Shad Telephone: (21) 4819010 Ext:303 |
Over 15 international research publications. 52 presentations in international conferences. She is also a conjoint professor of UAE University, UAE and University of New South Wales, Sydney, Australia. She is interested in investigating “Biological Markers for Metabolic Mental Disorders” using techniques and protocols of electrophysiology (e.g. patch clamping), mutagenesis coupled with single cell RT-PCR and biochemistry. She is also working on the "Protective Effect of SFE extracted Nigella sativa extract on petrochemical pollutant induced oxidative stress in vivo and in vitro" and “Diabetes associated altered cardiac function”.
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Prof. Dr.Iqbal Unnisa Ali
E-mail: iuali@iccs.edu |
Dr. Ali has worked as a senior scientist at the National Cancer Institute and subsequently, maintained an independent research program first at the National Institute of Neurological Disorders and Stroke and then at the Division of Cancer Prevention, National Cancer Institute. Her scientific work has been published in highly refereed journals. For the last several years, she and her co workers have conducted investigation using integrated genomic and proteomic approaches into the molecular mechanisms that underlie tumor initiation and progression in an effort to develop targeted molecular approaches to cancer prevention and intervention. Her ongoing work, using human clinical specimens and cultured cell lines, would help to develop a highly interactive molecular oncology program at the interface of basic, clinical, and translational research. The program is expected to make valuable contributions towards the goal of making individualized treatment a reality.
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Dr. Muhammad Kamran Azim E-mail:kamran.azim@iccs.edu |
12 Research publication in area of Proteolyric Enzymology. Recipient ofprestigious Alexander von Humboldt fellowship (Germany). Research interests include Structural Biology and Bioinformatics of proteases and their regulatory components with especial reference of the Proteosome; the intracellular protein degrading machinery.
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Dr. Shabana U.Simjee
E-mail:sh01us@hotamil.com |
Primary research focus is on issues related to chronic pain and chronicillness and the effects of persistent pain on brain neurotransmitter systems;.' Neuropharmacology of chronic pain; Exploring how neuropeptides and growth factors are involved in regulating inflammation and the immune and wound healing response.
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Dr. Zaheer-ul-Haq E-mail:zaheer.qasmi@iccs.edu |
30 research publications. Research focuses on computational chemistry and computer-based drug design specifically in areas of pharmaceutical and biomedical importance such as ligand-based drug design, protein flexibility and solvation effect in drug designing, ligand-protein and protein-protein interactions, designing of new bio-active molecules using computer aided modeling and ligand and structure based pharmacophore techniques. His research group specialize in molecular dynamics (MD) simulations, molecular docking, solvation energy, free energy of binding, QSAR, pharmacophore studies, in silico screening methods and ab initio calculations. Personal Webpage: Area of Research:
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Dr. Muhammad Ahmed Mesaik E-mail:mmesaik@hotmail.com |
10 research publications. His main research work include immuno-modulatory activity of natural compounds analyzing immune responses (stimulatory / inhibitory). Research interests include exploring how compounds suppress inflammatory cytokines involved in rheumatoid arthritis e.g. IL-1, TNF-γ by down regulating their production. He also manages immuno-modulatory, cytotoxicity and anti cancer screening activity besides the study of T and B cell response in relation to transplantation and graft rejection.
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Dr. Asmat Salim E-mail:salimasmat@yahoo.com |
8 research publications. Currently involved in the study of differentiation mechanisms of bone marrow derived stem cells into cardiac micro-environment both in vitro and in vivo. This includes stem cell isolation, propagation, identification and transplantation into theinfarcted heart and determination of their fate by functional analysis. The in vitro analysis includes studies related to fusion of different cell types in culture and analysis of the fused cells by identification of surface markers they express. Other research interests include protein structure studies and protein structure prediction.
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Dr. Huma Rasheed
E-mail: huma.rasheed@iccs.edu |
23 Research Publications. 35 abstracts in major Conferences and Symposia. The research project involves the over expression of tumor suppressor genes or anti-oncogenes that slow down cell division and repair DNA mistakes. The study deals with the design of transgenic expression vector, molecular cloning of the gene etc. The alteration in the expression of other regulated genes will also be investigated after the over expression of the gene of interest. Further studies will be done to investigate the novel synthetic and herbal compounds responsible for inhibiting the cell proliferation by inhibiting the proteins responsible for promoting cell division, by blocking epidermal growth factors or by inhibiting the other oncogenes. Other research areas include studies related to pain, inflammation and signaling/ cellular mechanism of thrombosis and hemostasis. She also has an experience to evaluate novel compounds for pharmacological and biochemical and toxicological activities.
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Dr. Shahida Shujaat E-mail: shahidashujaat@yahoo.com Telephone: (21) 4819010 Ext: 308 |
10 research publications. She is working on the isolation of bone marrow stem cells and classification of different bone marrow cell types on the basis of their surface antigens. Her research work also involves in vivo transplantation of stem cells to the infarcted myocardium of rats, measuring heart function after transplantation, analysis of formation of new blood vessels and other related techniques. She is also involved in the in vitro analysis of the co-culture of neonatal cardiomyocytes with bone marrow stem cells to investigate the relationship between in vivo transdifferentiation of bone marrow stem cells into new cardiomyocytes.
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Dr. Talat Makhmoor
Email: makhmoor@iccs.edu |
7 research publications. Her current research involves analysis of peptide antigen loading on the cells expressing Major Histocompatibilty Complexes (MHC) in the presence of catalytic amount of small organic compounds thus studying the cellular mechanisms involved in autoimmune reactions. Effective compounds can therefore be used as molecular tools in therapeutic settings. Research work also includes evaluation of anti-oxidant properties of organic compounds.
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Ms. Samreen Falak |
Current research studies involve analyses of complex cardiovascular diseases using rat as a model system. Main focus is directed towards the identification of underlying predisposing genes, subsequent identification of their molecular variants and establishing multiple congenic rat strains and molecular analysis. Research work also includes a combinatorial approach of positional cloning and expression profiling which serve as a powerful tool to identify positional candidate genes within chromosomal regions for genetically determined cardiovascular diseases.
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Mr. Muhammad Waqar Hameed |
Current research includes investigation of transcriptional and translational regulation of the expression of mitochondrial genes using microarrays. Genetic modification of genes encoding mitochondrial proteins include the cloning and subsequent over expression or silencing of genes of interest. Future investigations include measuring of ribosomal activity by polysome analysis and the effect of transgenic approaches on the mitochondrial energy production mechanism.
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Dr. Muhammad Hafizur Rahman E-mail:hafizbirdem@yahoo.com |
4 Research Publications, 20 abstracts in major Conferences and Symposia. Current research projects involve developing animal models of type 2 diabetes and investigating the effects of natural products in diabetic model rats. The study deals with any histological change(s) of the Pancreas that may occur and whether these changes can be prevented by different natural products. Further investigations will be focused on mainly regeneration/neogenesis of pancreatic Beta-cells and whether natural products have any role in regeneration/neogenesis of the pancreatic Beta-cells of model diabetic rats.
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Dr. Rafat Ali Siddiqui
E-mail:rsiddiqu@clarian.org |
Current research interests include studies of pulmonary angiogenesis by protein and lipid angiogenic factors and the role of omega-3 fatty acids (a constituent of fish oil) and polyphenols (found in grape skins and red wine) on cellular processes in cancer and the cardiovascular system.
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Prof. Dame Louise N. Johnson
E- mail:Louise.Johnson@biop.ox.ac.uk |
Louise Johnson read Physics at University College London and completed her PhD in Molecular Biophysics at the Royal Institution London (1965) under the supervision of Sir Lawrence Bragg and David Phillips where she worked on the structure of lysozyme, the first enzyme structure to be solved by X-ray diffraction. She joined the Laboratory of Molecular Biophysics at the University of Oxford in 1967. Her recent research has been with protein kinases and the regulatory molecules of the cell cycle and has included a structure based drug design programme. She was appointed to the David Phillips Chair of Molecular Biophysics in Oxford in 1990 and was elected Fellow of the Royal Society also in 1990. In 2003 she was appointed Director of Life Sciences at the Diamond Light Source, the UK's new synchrotron source and shares this position 50% with her appointment at Oxford. In 2003 she was awarded the title of DBE in the New Years Honors list.
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Dr. Farooq Rahman Soomro
E-mail: dr_farooq_02@yahoo.com |
Dr. Soomro is currently working as Senior Medical Officer (BPS-18) Incharge Leprosy Control Centre near Atta Turk Tower Larkana and for HIV/AIDS, Sindh Blood Transfusion Authority, Leishmaniasis at EDO health office Larkana. He is also Honorary Medical Consultant, Marie Adelaide Leprosy Centre Karachi. He has published many research papers in the field of dermatology especially leishmaniasis and Leprosy.
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Professor Saadiya Aziz Karim
E-mail: saadiya.aziz@gmail.com |
Prof. Saadiya Aziz Karim is the Dean, Faculty of Medicine, University of Karachi. She is also the Chairperson, Obstetrics and Gynaecology, at Karachi Medical & Dental College and Abbasi Shaheed Hospital and former Principal, Karachi Medical & Dental College. She has played a pivotal role in the development of Undergraduate and Postgraduate training programmes and Research at the Aga Khan University, University of Karachi and the College of Physicians & Surgeons, Pakistan. She has been awarded Honorary Fellowship of the College of Physicians & Surgeons, Pakistan in consideration of long standing national service to the medical profession. Author of 24 publications, including original research and chapters in international books, her current research focuses on relationship of nutritional parameters with pregnancy outcome and development of national screening programs for gynaecological cancer.
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